Stiff Person Syndrome

In some cases the muscles of the neck trunk and shoulders may also be. Stiff Person Syndrome SPS is an autoimmune and neurological disorder that can make the muscles in the torso and limbs alternate between rigidity and spasms.

Stiff Person Syndrome Practical Neurology

But more people are affected than reported due to misdiagnoses.

. SPS is labeled as a rare disease. Stiff-person syndrome SPS is a rare and disabling central nervous system disorder with no satisfactory treatment. Symptoms may include extreme muscle stiffness rigidity and painful spasms in the trunk and limbs severely impairing mobility.

Symptoms include muscle spasms hyper-rigidity debilitating pain and chronic anxiety. Affected individuals also develop involvement of the brainstem which can cause myoclonus. Stiff person syndromeMoerschWoltmann syndrome or SPS is an extremely rare and progressive neurological disorder that impacts the nervous system of the body.

Stiff person syndrome SPS is a rare progressive syndrome that affects the nervous system specifically the brain and spinal cord. Muscle rigidity sporadic muscle spasms and chronic muscle pain characterize SPS. SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise touch and emotional distress which can set off muscle spasms.

The cause of this extremely rare disease is still unknown. The stiffness primarily affects the truncal muscles and is superimposed by spasms resulting in postural deformities. The disorder is often stimulated by emotional stress.

Stiff-person syndrome SPS is a rare neurological disorder with features of an autoimmune disease. Why Choose Johns Hopkins. Stiff person syndrome SPS is a very rare disease affecting only one or two people per million.

SPS is strongly correlated with autoimmune diseases and it is usual to find high titers of antibodies against acid decarboxylase GAD65. Stiff person syndrome is more likely seen in people with certain types of diseases including. Certain cancers including breast lung kidney thyroid colon and Hodgkins lymphoma.

Muscle spasms can be so violent they can dislocate joints and even break bones. Spasms can generate enough force to fracture bone. Stiff-person syndrome SPS also known as stiff-man syndrome SMS 1 is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness.

Autoimmune disorders including diabetes thyroiditis vitiligo and pernicious anemia. Jerking stiff-person syndrome is characterized by muscles stiffness and spasms usually affecting the legs. The disorder generally impacts the spine and extreme lower parts of the body.

Stiff person syndrome SPS is a neurological disease with autoimmune features. Myoclonus is a general term used to describe the sudden involuntary jerking of a muscle or group of muscles caused by muscle contractions positive myoclonus or. It causes progressive muscle stiffness and painful spasms that can be triggered by a variety of things including sudden movement cold temperature or unexpected loud noises.

Stiff Person Syndrome Practical Neurology

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